Gamarra S, Morano S, Dudiuk C, Mancilla E, Nardin ME, de Los Angeles Méndez
E, Garcia-Effron G. 2014. Epidemiology and antifungal susceptibilities of yeasts causing vulvovaginitis in a teaching hospital. Mycopathologia. Epub ahead of print Jul 9. Abstract.
Dudiuk C, Gamarra S, Leonardeli F, Jimenez-Ortigosa C, Vitale RG, Afeltra
J, Perlin DS, Garcia-Effron G. 2014. Set of Classical PCRs for detection of mutations in Candida glabrata FKS genes linked with echinocandin resistance. J Clin Microbiol. Jul; 52(7): 2609-14. Abstract.
Datta K, Rhee P, Byrnes E 3rd, Garcia-Effron G, Perlin DS, Staab JF, Marr KA. 2013. Isavuconazole activity against emerging fungal pathogens with reduced azole-susceptibility: Aspergillus lentulus, Neosartorya udagawae and Cryptococcus gattii.
J Clin Microbiol. 2013 Sep; 51 (9): 3090-93. Texto completo.
Gamarra S, Dudiuk C, Mancilla E, Vera Garate MV, Guerrero S,
Garcia-Effron G. 2013. Molecular
tolos for cryptic Candida species identification with applications in a
clinical laboratory. Biochem Mol Biol Educ. May-Jun; 41(3):180-6. Abstract.
García-Effron G, Canton
E, Pemán J, Dilger A, Romá E, Perlin DS. 2012. Epidemiology and echinocandin susceptibility
of Candida parapsilosis sensu lato species isolated from blood stream
infections at a Spanish University Hospital. Journal of Antimicrobial Chemotherapy. Nov; 67(11):2739-48. Texto Completo.
Pratt A, Garcia-Effron G, Zhao Y, Park S, Mustaev A, Pillai S, Perlin DS. 2012. Evaluation of fungal-specific fluorescent labeled echinocandin probes as diagnostic adjuncts. Med. Mycol. Jan; 51(1): 103-7. Abstract.
Bartoli MZ, Cingolani B, García-Effron G, Gamarra S. 2011. Análisis de métodos fenotípicos para la diferenciación de Candida dubliniensis y Candida albicans. Propuesta de una secuencia de identificación. Revista FABICIB. 2011. 15: 138-149. Texto completo.
García-Effron G, Canton E, Pemán J, Dilger A, Romá E, Perlin DS. 2011. Assessment of two new molecular based methods for identification of Candida parapsilosis sensu lato species. 2011. Journal of Clinical Microbiology. 49(9):3257-61. PMID: 21795509. Texto completo.
Ben-Ami R, Garcia-Effron G, Lewis RE,
Gamarra S, Leventakos K, Perlin DS, Kontoyiannis DP. 2011. Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with
echinocandin resistance. J. Infect.
Dis. 204 (4): 626-35. PMID: 21791665.
García-Effron G, Park S, Perlin DS. Improved detection of Candida spp. fks
hot spot mutants using the CLSI M27-A3 Document by the addition of Bovine
Serum Albumin (BSA). Antimicrob Agents Chemother. 2011. 55(5):2245-55. PMID: 21383097. Texto completo.
Arendrup M, Rodriguez-Tudela JL, Park S, García-Effron G, Delmas G,
Cuenca-Estrella M, Gomez-Lopez A, Perlin DS. Echinocandin susceptibility testing of Candida
spp. using the EUCAST EDef 7.1 and CLSI M27-A3 standard procedures:
Analysis of the influence of Bovine Serum ALbumin Suplementation, Storage
Time and Drug Lots. Antimicrob Agents Chemother. 2011.
55(4):1580-7. PMID: 21245440.
Gamarra S y García-Effron G. Evolución de la producción científica de
Argentina en microbiología entre los años 1987 y 2009. Revista FABICIB.
2011. 14: 209-223. Texto completo.
Zhang YQ, Gamarra S, García-Effron G, Park S, Perlin DS, Rao R. Requirement for ergosterol in V-ATPase
function underlies antifungal activity of azole drugs. PLoS Pathog.
2010. Jun 3; 6(6): e1000939. PMID: 20532216. Texto completo.
Rodriguez-Tudela JL, Gomez-Lopez A, Arendrup MC, García-Effron G,
Perlin DS, Lass-Flörl C, Cuenca-Estrella M. Comparison of Caspofungin MICs by means of
EUCAST EDef 7.1 using two different concentrations of glucose. Antimicrob
Agents Chemother. 2010. Jul; 54(7): 3056-7. PMID; 20479199. Texto completo.
Pfeiffer CD, García-Effron G, Zaas AK, Perfect JR, Perlin DS,
Alexander BD. Breakthrough Invasive Candidiasis on Micafungin. J Clin
Microbiol. 2010. Jul; 48 (7): 2373-80. PMID: 20421445.
García-Effron G, Chua
DJ, Tomada JR, Dipersio J, Perlin DS, Ghannoum M, Bonilla H. Novel FKS Mutations Associated with Echinocandin Resistance
in Candida Species. Antimicrob Agents Chemother. 2010. May;
54(5):2225-7. PMID: 20145084.
Gamarra S, Rocha EM, Zhang YQ, Park S, Rao R, Perlin DS. Mechanism of the synergistic effect
of amiodarone and fluconazole in Candida albicans. Antimicrob Agents Chemother. 2010 May;54(5):1753-61. Epub 2010 Mar 1.PMID: 20194694. Texto completo.
Martínez-López J, Crooke A, Grande S, Ayala R, Jiménez-Velasco A, Gamarra S, Meneu JC, Gilsanz F. Real-time PCR quantification of
haematopoietic chimerism after transplantation: a comparison between TaqMan and
hybridization probes technologies. Int J Lab Hematol. 2010 Feb;32(1 Pt 1):e17-25. Epub 2009 May 12. PMID: 19453606. Texto completo.
Arendrup MC, García-Effron
G, Lass-Flörl C, Lopez AG, Rodriguez-Tudela JL, Cuenca-Estrella M, Perlin
DS. Echinocandin Susceptibility Testing of Candida
species: Comparison of EUCAST EDef 7.1, CLSI M27-A3, Etest, Disk
Diffusion, and Agar Dilution Methods with RPMI and Isosentistest Media. Antimicrob
Agents Chemother. 2010. Jan; 54(1):426-39. PMID: 19884370. Texto completo.
Gamarra S, García-Effron G,
Monteserin C, Lopez-Villar I, Gilsanz F, Martinez-Lopez J. 2009. β-ThalassaemiaMajor in a Spanish Patient due to
a Compound Heterozygosity for CD39 C → T/−28 A → C. Advances in
Hematology. 2009: 476342. PMID:
19960060.
García-Effron G, Lee S, Park S, Cleary JD, Perlin DS. Effect of Candida glabrata FKS1 and
FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-b-D-glucan synthase: implication for the
existing susceptibility breakpoint. Antimicrob Agents
Chemother. 2009. Sep; 53(9):3690-9. PMID: 19546367.
Arendrup MC, García-Effron G, Buzina W, Mortensen KL, Reiter N,
Lundin C, Jensen HE, Lass-Flörl C,
Perlin DS, Bruun B. Breakthrough Aspergillus
fumigatus and Candida albicans double infection during
caspofungin treatment: laboratory characteristics and implication for
susceptibility testing. Antimicrob Agents Chemother. 2009. Mar;
53(3): 1185-93.PMID: 19104024. Texto completo.
García-Effron G, Park S, Perlin DS. Correlating Echinocandin MIC and Kinetic
Inhibition of fks1 Mutant Glucan Synthases for Candida albicans: Implications for Interpretive Breakpoints. Antimicrob Agents Chemother. 2009. Jan; 53 (1): 112-22.
PMID: 18955538. Texto completo.
García-Effron
G, Kontoyiannis DP, Lewis RE, Perlin DS. Caspofungin-resistant Candida
tropicalis strains causing breakthrough fungemia in patients at high
risk for hematologic malignancies. Antimicrob
Agents Chemother. 2008 Nov; 52(11):
4181-3. PMID: 18794386. Texto completo.
Wiederhold NP, Grabinski JL, García-Effron G, Perlin DS, Lee SA. Pyrosequencing to detect mutations in FKS1
that confer reduced echinocandin susceptibility in Candida
albicans. Antimicrob Agents
Chemother. 2008 Nov; 52(11): 4145-8. PMID:
18794385. Texto completo.
Arendrup MC, Perkhofer S, Howard AJ, García-Effron G, Kumar V,
Perlin DS, Latgè JP, Lass-Flörl C. Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins. Antimicrob Agents Chemother. 2008
Oct;52(10):3504-11. PMID: 18644959. Texto completo.
García-Effron G, Katiyar S, Park S, Edlind TD, Perlin DS. A naturally ocurring Proline-to-Alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis accounts for reduced echinocandin susceptibility. Antimicrob Agents Chemother. 2008 Jul; 52(7): 2305-12. PMID: 1844311.
García-Effron G, Katiyar S, Park S, Edlind TD, Perlin DS. A naturally ocurring Proline-to-Alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis accounts for reduced echinocandin susceptibility. Antimicrob Agents Chemother. 2008 Jul; 52(7): 2305-12. PMID: 1844311.
Cleary JD, García-Effron G, Chapman SW, Perlin DS. Caspofungin resistance in Candida glabrata secondary to a FKS1 mutation developed during candidemia treatment. Antimicrob Agents Chemother. 2008 Jun; 52 (6): 2263-5. PMID: 18378714.
García-Effron G, Dilger A, Alcazar-Fuoli L, Park S, Mellado E,
Perlin DS. Rapid
detection of triazole antifungal resistance in Aspergillus fumigatus. Journal of Clinical Microbiology. 2008 Apr; 46 (4): 1200-6. PMID: 18234874.
Alcazar-Fuoli
L, Mellado E, García-Effron G, Lopez JF, Grimalt JO, Cuenca-Estrella JM,
Rodriguez-Tudela JL. Ergosterol
biosynthesis pathway in Aspergillus
fumigatus. Steroids. 2007
73 (3): 339-347. PMID: 18191972. Abstract.
Rocha EM, García-Effron G, Park S, Perlin DS. A Ser678Pro substitution in Fks1p confers
resistance to echinocandin drugs in Aspergillus
fumigatus. Antimicrob Agents
Chemother. 2007. 51(11):4174-6.
PMID: 17724146. Texto completo.
García-Effron G, Gamarra S, Crooke Alvarez A, Martinez-Sanchez P,
Lahuerta-Palacios J, Martinez-Lopez J.
Comparison of the MagNA Pure LC Automated System and the Ribo Pure – Blood
RNA Manual Method for RNA Extraction from Multiple Myeloma Bone Marrow
Samples Conserved in an RNA stabilizer. Int. J. Lab. Hematol. 2007.
29: 139–144. PMID: 17474887. Texto completo.
Paderu P, García-Effron
G, Balashov S, Delmas G, Park S, Perlin DS. Serum
differentially alters the antifungal properties of echinocandin drugs. Antimicrob
Agents Chemother. 2007. 51(6): 2253-6. PMID: 17420211. Texto completo.
Mellado E, García-Effron G, Alcazar-Fuoli L,
Melchers WJ, Verweij PE, Cuenca-Estrella M, Rodriguez-Tudela JL. A new Aspergillus fumigatus resistance
mechanism conferring in vitro cross-resistance to azole antifungals
involves a combination of cyp51A
alterations. Antimicrob Agents Chemother. 2007. 51(6): 1897-904.
PMID: 17371828.
Kahn JN, García-Effron
G, Hsu MJ, Park S, Marr KA, Perlin DS. Acquired
echinocandin resistance in a Candida
krusei isolate due to modification of glucan synthase. Antimicrob Agents Chemother. 2007.
51(5): 1876-8. PMID: 17325225. Texto completo.
Mellado E, Alcazar-Fuoli L, García-Effron G,
Alastruey-Izquierdo A, Cuenca-Estrella M, Rodríguez-Tudela JL. New resistance mechanisms to azole drugs in Aspergillus
fumigatus and emergence of antifungal drugs-resistant A. fumigatus atypical
strains. Medical Mycology. 2006.
44 Suppl:367-71.
Quintela-Fandino M, Hitt R, Medina PP, Gamarra S, Manso L, Cortes-Funes H, Sanchez-Cespedes M. DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy. J. Clin. Oncol. 2006. 24 (26): 4333-9. PMID: 16896002. Texto completo.
Quintela-Fandino M, Hitt R, Medina PP, Gamarra S, Manso L, Cortes-Funes H, Sanchez-Cespedes M. DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy. J. Clin. Oncol. 2006. 24 (26): 4333-9. PMID: 16896002. Texto completo.
Martinez-Lopez J, Martinez-Sanchez P, García-Sanz R,
Sarasquete ME, Ayala R, Gonzalez M, Bautista JM, Gonzalez D, San Miguel J,
García-Effron G, Lahuerta JJ. Application
of self-quenched JH consensus primers for real-time quantitative PCR of
IgH gene to minimal residual disease evaluation in multiple myeloma. Journal
of Molecular Diagnostics. 2006.
8(3):364-70. PMID: 16825510. Abstract.
Quintela-Fandino M, López JM, Hitt R, Gamarra S, Jimeno A, Ayala R, Hornedo J, Guzman C, Gilsanz F, Cortés-Funes H. Breast cancer-specific mRNA transcripts presence in peripheral blood after adjuvant chemotherapy predicts poor survival among high-risk breast cancer patients treated with high-dose chemotherapy with peripheral blood stem cell support. J. Clin. Onclo. 2006. 24 (22):3611-8. PMID: 16877728. Texto completo.
Quintela-Fandino M, López JM, Hitt R, Gamarra S, Jimeno A, Ayala R, Hornedo J, Guzman C, Gilsanz F, Cortés-Funes H. Breast cancer-specific mRNA transcripts presence in peripheral blood after adjuvant chemotherapy predicts poor survival among high-risk breast cancer patients treated with high-dose chemotherapy with peripheral blood stem cell support. J. Clin. Onclo. 2006. 24 (22):3611-8. PMID: 16877728. Texto completo.
Cuenca-Estrella M, Gomez-Lopez A, Buitrago MJ, Mellado E, García-Effron G, Rodriguez-Tudela JL. In vitro activities of 10 combinations of antifungal agents against
the multiresistant pathogen Scopulariopsis brevicaulis. Antimicrob
Agents Chemother. 2006. 50(6):2248-50. PMID: 16723597. Texto completo.
Alcazar-Fuoli L,
Mellado E, García-Effron G, Buitrago MJ, Lopez J, Grimalt J,
Cuenca-Estrella M, Rodriguez-Tudela
JL. Aspergillus
fumigatus C-5 sterol desaturases (Erg3A and
Erg3B): role in sterol biosynthesis and antifungal drugs susceptibility. Antimicrob
Agents Chemother. 2006. 50(2):453-60. PMID: 16436696.
Cuenca-Estrella M, Gomez-Lopez A, Mellado E, García-Effron
G, Monzon A, Rodriguez-Tudela JL. In
vitro activity of ravuconazole against 923 clinical isolates of
nondermatophyte filamentous fungi. Antimicrob Agents Chemother.
2005. 49(12):5136-8. PMID: 16304186. Texto completo.
Mellado E, García-Effron
G, Buitrago MJ, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Targeted gene disruption of the 14-alpha sterol demethylase
(cyp51A) in Aspergillus fumigatus and its role in azole drugs
susceptibility. Antimicrob Agents Chemother. 2005. 49(6):2536-8. PMID:
15917566. Texto completo.
García-Effron G, Mellado E, Gomez-Lopez A,
Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Differences in interactions between azole drugs related to
modifications in the 14-alpha Sterol Demethylase Gene (cyp51A) of Aspergillus
fumigatus. Antimicrob Agents Chemother. 2005. 49(5):2119-21.
PMID: 15855543. Texto completo.
Cuenca-Estrella M, Gomez-Lopez A, García-Effron
G, Alcazar L, Mellado E, Buitrago MJ, Rodriguez-Tudela JL. Combined activity in vitro of caspofungin, amphotericin B and azole
agents against itraconazole resistant clinical isolates of Aspergillus fumigatus. Antimicrob Agents Chemother. 2005.
49(3):1232-5. PMID:
15728937. Texto completo.
Cuenca-Estrella M, Gomez-Lopez A, Mellado E, García-Effron
G, Rodriguez-Tudela JL. In
vitro activities of ravuconazole and four other antifungal agents against
fluconazole-resistant or -susceptible clinical yeast isolates. Antimicrob
Agents Chemother. 2004. 48(8):3107-11.
PMID: 15273127. Texto completo.
Mellado
E, García-Effron G, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela
JL. Substitutions at
methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus
fumigatus are responsible for resistance in vitro to azole antifungal
drugs. Antimicrob Agents Chemother. 2004.
48(7):2747-50. PMID: 15215142.
García-Effron G, Gomez-Lopez A, Mellado E,
Monzon A, Rodriguez-Tudela JL, Cuenca-Estrella M. In vitro activity of terbinafine against
medically important non-dermatophyte species of filamentous fungi. J
Antimicrob Chemother. 2004. 53(6):1086-9.
PMID: 15102749. Texto completo.
Gomez-Lopez A, García-Effron G, Mellado E,
Monzon A, Rodriguez-Tudela JL, Cuenca-Estrella M. In vitro activities of three licensed antifungal
agents against spanish clinical isolates of Aspergillus spp. Antimicrob
Agents Chemother. 2003. 47(10):3085-8. PMID: 14506013. Texto completo.
Cuenca-Estrella M, Rodero L, García-Effron G,
Rodríguez-Tudela J. Antifungal susceptibilities of Candida
spp. Isolated from blood in Spain and Argentina, 1996
– 1999. Journal of Antimicrobial Chemotherapy. 2002. 49: 981 – 987. PMID: 12039890. Texto completo.
Sarsotti P,
Hernandez A, Pawluk D, Gutierrez C, García-Effron G, Seba-Ponzoni C. Cyclospora
cayetanensis: Un protozoo emergente en expansión. Primer caso en Santa Fe,
Argentina. Revista FABICIB. 2002. 6: 153-54. Texto completo.
García-Effron
G, Gutierrez C, Sarsotti P, Vanni C. Determinación de la variedad
en cepas de Cryptococcus neoformans del cepario de la Cátedra de Micología de
la Facultad de Bioquímica y Ciencias Biológicas de la Universidad Nacional
del Litoral. Revista FABICIB. 2001.
5: 57-59. Texto completo.
Vanni C,
Sarsotti P, Ruatta J, García-Effron G, Gutiérrez C, Cabagna M. Ecología del Cryptococcus
neoformans en Santa Fe (Argentina). Revista FABICIB. 1998. 2:
25-30. Texto completo.
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